In these notes and commentaries on the book Lifespan, we’ll be focusing more on the practical side of David Sinclair’s ideas, less on the scientific theory and moral discussion. Greater longevity will affect every part of our world, from population growth to career planning to social security programs. Here Sinclair imagines what a future with lots of 120-year-olds will look like. Part 3 talks about future implications of living longer.Sinclair says our ‘longevity genes’ are activated through practices like calorie restriction, fasting, exercise and cold exposure… and promising medicines are being studied that could become future anti-aging treatments. Today, scientists are studying many pathways for extending lifespan and there are many exciting results to share, but there is also still much they don’t know. Part 2 talks about current research and treatments. ![]() (Don’t worry, we’ll explain what that means later.) That is good news because it means we may be able to slow and-who knows-maybe eventually stop aging altogether. His current theory is that aging is really a loss of information in our epigenome. ![]() ![]() Sinclair tells the story of how our scientific understanding of aging has evolved over the last few decades. This book Lifespan is split into 3 parts: We all want to live a long and healthy life, right? The problem is that getting older often means becoming more frail and chronically ill-and none of us want that! Well, good news! Right here, we’ll be exploring the latest science about how we may be able to extend not just our life, but our healthy years of life.
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